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01 Diagnosis Before Protocol Dull skin caused by dehydration requires a fundamentally different treatment to dull skin caused by melanin accumulation or collagen loss

Endocrinol Jpn 22:483, 1975

L-Cystine : Gip gim s hnh thnh melanin, h tr ci thin cc vt thm sm, tn nhang

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It directly inhibited the stearoyl-CoA desaturase-1 (SCD1) protein to trigger ferroptosis of ovarian cancer, evidenced by the increased ROS, total iron, and Fe 2+ levels and downregulation of ferroptosis inhibitors (SLC7A11 and GPX4), thus suppressing cancer progression in the SKOV-3 xenograft model (Liu et al., 2022)

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