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[DOI] [PMC free article] [PubMed] [Google Scholar] 155.Du J., Cieslak J.A., III, Welsh J.L., Sibenaller Z.A., Allen B.G., Wagner B.A., Kalen A.L., Doskey C.M., Strother R.K., Button A.M., et al

After washing with 6 mL H 2 O and additional 6 mL n -hexane, oxylipins were eluted with 6 mL methyl formate

[PubMed: 18411172] 60

In a type 1 diabetic Akita mouse model, which was used as a nonobese insulin-dependent model of spontaneous type 1 diabetes, empagliflozin treatment attenuated diabetes-induced rise in renal expression of markers of kidney growth by reducing the cyclin-dependent kinase inhibitors p27 and p21, which were over-expressed in early diabetic kidneys (152)