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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations

While both Vitamin B12 injections and oral supplements have their place, the decision ultimately comes down to your unique health needs

Authors conclusions: Low quality evidence shows oral and IM vitamin B 12 having in terms of normalizing serum vitamin B similar effects 12 levels, but

Tax benefits with an HSA may be administered that way but there are also other options

The site of injection will also vary depending on many factors

The four below sit closest to it in research community use