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The most consistent finding: researchers who dose MOTS-c in the morning during fasted states report more pronounced shifts in substrate utilizationmeasured via respiratory exchange ratio (RER)than those administering it post-meal

Others experience gradual benefits over several weeks of consistent use

This group has also recently reported (2025) that intravenous administration of BPC 157 had no side-effects and was well-tolerated in two women

We thought we could avoid the melting because that enzyme naturally can survive those high temperatures since the bacteria live in thermal vents, Rustgi said

10.1136/bmj.i4919 [DOI] [PMC free article] [PubMed] [Google Scholar] Sterne J

Aging-related decline