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the original rodent study used 5 mg/kg, which when scaled allometrically to human equivalents suggests doses in the 5-10 mg range for a 70 kg adult, though allometric scaling from mice to humans is an imprecise science

Metformin in cancer treatment and prevention

Ab0475 Transcranial Direct Current Stimulation Decreases Chronic Pain in Patients with Rheumatoid Arthritis: A Randomized, Controlled, Double-Blind Clinical Trial

doi: 10.1002/rmv.2221 200 MuraeM.ShimizuY.YamamotoY.KobayashiA.HouriM.InoueT.et al

Some patients notice benefits such as increased energy or brighter skin after a few sessions

Qiu W, Hu M, Sridhar A, Opeskin K, Fox S, Shipitsin M et al