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Contrary to most other leading causes of mortality, there is no effective treatment for AD and efforts to find effective treatments have met with limited success in part because the focus has been on testing drugs that target a specific pathogenic mechanism

Gaudreault-Tremblay M-M, Foster BJ (2020) Benefits of continuing RAAS inhibitors in advanced CKD

Oligodendrocytes, their progenitors and other neuroglial cells in the aging primate cerebral cortex

Levocarnitine may alleviate the metabolic abnormalities of patients with inborn errors that result in accumulation of toxic organic acids

The first is eumelanin, which is responsible for dark brown and black pigments

however, the exact mechanisms by which UA interacts with misfolded proteins remain unclear