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In mouse models of highfat dietinduced obesity, it treatment significantly reduced mRNA and protein expression of TNF, IL6, and other inflammatory factors in adipose tissue and decreased macrophage infiltration - a hallmark of adipose inflammation

Vegetarians and vegans, you probably need supplemental B12

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Who Benefits from B12 Injections

However, few studies have examined the relationship of vitamin B 12 status, homocysteine concentrations, and the development of depression over time