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Structurally, the product was optimized on the basis of exenatide, and the glycine 2, methionine 14 and asparagine 28 positions were modified to improve enzyme stability and chemical stability based on the polypeptide backbone

Dihexa was administered to aduts male Sprague Dawley rats at lOmg/kg

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Quick Answer: Tirzepatide burning at injection site is a recognized adverse reaction occurring in approximately 3.4% of patients, typically caused by the medication's formulation pH, tissue distension, or individual sensitivity, and usually resolves spontaneously within minutes to hours

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