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DOX group To create the POI rat model, rats were given doxorubicin (DOX, 2.5 mg/kg

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Both magnesium and taurine regulate calcium handling in muscle cells

The experimental design involved pre-treatment of primary hepatic cells with SAG (at 0.25, 0.5, 0.75, 1.0, 1.25, 1.5 or 2.00 mM, dissolved in saline as stock solution and diluted in DMEM) for 1 h followed by exposure to CCl4 (4 mM diluted in 0.5% DMSO) for 6 h