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with 25, 12.5, 6.25, and 3.125 mg/kg of body weight (bw) rosiglitazone (PPAR agonist) and 3.125 mg/kg bw WY-14643 (PPAR agonist) or a combination of rosiglitazone (25 mg/kg bw) and WY-14643 (12.5 mg/kg bw) to assess the cardiac PPAR coactivator 1- ( Ppargc1a ) mRNA levels ( n = 616)

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The Gerson therapy has three major components: diet detoxification supplements People on the therapy must follow an organic, plant-based diet with raw juices, use coffee enemas several times daily for detoxification, and take a wide variety of supplements

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Although examination of fecal polymicrobial cultures indicates both the presence and dietary induction of fecal microbial BBTMA transforming activity, the microbial gene(s) encoding this enzyme activity, an important potential therapeutic target, remain unknown