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Despite the antitumor effect of erastin, evidence has also shown that iron concentration and macrophage polarization in the tumor microenvironment promote the resistance of ovarian cancer cells to erastin-induced ferroptosis

Rong et al., 2022

ROS and antimicrobial activities One of the major factors that leads to the formation of chronic wounds is that of prolonged inflammation and pathogenic infection, which can hamper angiogenesis, stem cell function, and extracellular matrix remodelling 93

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Supplementing with Glutathione Glutathione supplementation has mostly been reserved for clinical use due to its high cost and lack of access

This is meaningful early-phase data, but it falls far short of the Phase III trial evidence that would be required for FDA approval