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Discussion Lysosome positioning and dynamics are crucial for nearly all aspects of lysosome function in health and disease, ranging from autophagy 43 and the cellular response to nutrient starvation 1,2,3 to lysosomal exocytosis during membrane repair 44 , cancer 43,45 , and neurodegeneration, e.g., Alzheimers or Parkinsons disease, which are associated with the accumulation of stalled defective lysosomes in axonal varicosities 1,9,46

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When antioxidant systems fail and the redox balance shifts toward oxidation, an increase in the concentration of salivary lipid peroxidation products generated by non-enzymatic pathways is observed (Guentsch et al., 2008

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