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[2] Exposure to nitrous oxide (including recreational use) can cause functional B12 deficiency and worsen neurological manifestations

Community-reported effects (nausea, GI discomfort, headache) come only from anecdotal vendor/forum sources, not controlled studies

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One of the most significant of these is the activation of SIRT1, often called a longevity gene. SIRT1 helps manage insulin sensitivity and supports healthier blood sugar regulation, which is fundamental for sustained energy and preventing the metabolic strain that can lead to weight gain

Reconstituted at 2-8C, use within 60 days

Demonstrated proof-of-concept for the dual agonist approach Phase 1b/2a (SC): Up to 24% weight loss at 36 weeks with doses up to 60 mg