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The specific time of day does not significantly affect efficacy, but consistency helps establish a routine

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However, it should be noted that one study failed to find beneficial effects of vitamin D supplementation in patients with ASD, although sample size in this trial is relatively small 42

10.1038/nrc3278 Pubmed Abstract CrossRef Google Scholar View reference in article 21

- Tolerancia transitoria a temperatura ambiente: hasta 30 das sin prdida funcional significativa documentada en bioensayos

Juanpablo - it could still be worth finding out what your current B12 reading is , if you can find a medical professional who understands that it should by now be very high