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10.1021/acssynbio.1c00402
This study employed various experimental methods to develop peptides that inhibit interactions between FOXO4 and p53
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Moreover, it was postulated that the aromatic ring of the 3-homotyrosine side chain and the C-terminal phenyl ring interact and Phe550 in IRAP further stabilizes aromatic/hydrophobic packing ( More recently, a crystal structure of IRAP with the macrocyclic peptide inhibitor 23 (HA08) was reported (Mpakali et al., 2020)
Hoffmann T
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