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Normal mice in this experiment usually showed less violent movements and were more likely to interact with the newcomer, the intruder 54,55

Moreover, mitochondrial DAMPs released from stressed cells-such as mtDNA and cardiolipin-serve as potent activators of pattern recognition receptors (e.g., TLR9, cGAS-STING, and NLRP3), perpetuating inflammation (Mills et al., 2017)

Inactive form

The LR3 modification gives it a much longer half-life (20-30 hours vs

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Exploring the home healthcare workforce in Alzheimer's disease and related dementias: Utilization and cost outcomes in US community dwelling older adults