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Cancer Res 77(23):67466758 Akins NS, Nielson TC, Le HV (2018) Inhibition of glycolysis and glutaminolysis: an emerging drug discovery approach to combat cancer

The ladder above is not a validated human dose

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Those ligand-target bindings would include benzodiazepine, opioid, (1)- and (2)-adrenergic, serotonergic and cholinergic receptors 85 and, notably, the fascinating issue of the anti-nociceptive role of melatonin seems to be mediated by MT1 and MT2 receptors themselves 86 , 87,88

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doi:10.1016/S0002-9378(98)70645-3