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For example, in MS-DRG 166, there are 826 cases reporting a principal diagnosis of PE and USAT procedure with the administration of thrombolytic(s) and 161 cases reporting a principal diagnosis of PE and USAT procedure without the administration of thrombolytic(s), however, both subsets of cases have an equivalent average length of stay of 5.4 days and a difference in average costs of $1,015 ($28,912$27,897 = $1,015)

Acknowledgments The authors would like to thank the biological Science Department of Peking ChipStone for helpful on the figure conduction related to this work Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Disruptions in iron's intake, transport, storage, or utilization can activate the Fenton reaction, leading to a surge of ROS and hydroxyl radicals [127]

Altered microbial 5-HT modulation is linked to mood disorders, with deficiencies associated with depression and anxiety (Loh et al., 2024)

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