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In an effort to eliminate the bacteria, both neutrophils and macrophages phagocytose produce ROS

12.6 Anaerobic glycolysis in yeast

(PubMed) McNulty H, Strain JJ, Hughes CF, Pentieva K, Ward M

The combination creates synergy through complementary mechanisms

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The precise programming of bacterial behavior through synthetic biologysuch as tumor microenvironment-responsive or near-infrared-controlled systemscombined with artificial intelligencedriven predictive tools, may transform locally administered living bacteria into practical therapeutic weapons against cancer