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The authors described any possible symptomatic effect as preliminary and requiring a larger study

Carcinogenesis 8:5966 Powers R (2009) NMR metabolomics and drug discovery

A 2019 review in the Journal of Physiology noted that "IGF-1 signalling and mechanical loading converge on mTORC1 to regulate skeletal muscle protein synthesis, and the relative contribution of each remains an active area of investigation" [6]

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The ROC curves were generated for each enzyme individually, and a combined analysis using a multivariable logistic regression model was performed to assess the overall predictive value of these markers

10.1016/j.bpc.2023.107122 Biophys