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Category 2 designation means the substance presents "safety concerns" and is prohibited from being used in compounding by licensed pharmacies

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In klinische studies zijn bij aanbevolen doseringen weinig bijwerkingen gemeld

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GT-activated prodrugs and potential nephrotoxicity Gamma-glutamyl transferase being the initial and limiting step in GT-activated prodrugs processing and because GT is highly expressed on the luminal surface of the proximal tubules in the kidney, potential nephrotoxicity could have been a limitation in the usage of this class of compound when administered systematically

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Every therapy begins with a personalized consultation and medical evaluation

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Abdullah KM, Sharma G, Singh AP, Siddiqui JA (2025) Nanomedicine in Cancer Therapeutics, Current Perspectives from Bench to Bedside

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