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A 2004 study by Korkushko et al

Fibroblast and myofibroblast activation in normal tissue repair and fibrosis

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Giles FJ, Miller CB, Hurd DD, Wingard JR, Fleming TR, Sonis ST, Bradford WZ, Pulliam JG, Anaissie EJ, Beveridge RA, Brunvand MM, Martin PJ, PROMPT-CT Trial Investigators: A phase III, randomized, double-blind, placebo-controlled, multinational trial of iseganan for the prevention of oral mucositis in patients receiving stomatotoxic chemotherapy (PROMPT-CT trial)

Weekly doses, when used, may range from 600 to 1200 mg under supervision, but such use is not FDA-approved and must be approached cautiously