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Small, 2021, 17: 2102527 Gao G, Jiang Y, Guo Y, et al

doi: 10.1038/nri2572 521 Saulep-EastonDVincentFBQuahPSWeiATingSBCroceCMet al

doi: 10.1186/alzrt146

Biophys J 68(3):10271044 Chauveau C, Bonnemann CG, Julien C, Kho AL, Marks H, Talim B, Maury P, Arne-Bes MC, Uro-Coste E, Alexandrovich A, Vihola A, Schafer S, Kaufmann B, Medne L, Hbner N, Foley AR, Santi M, Udd B, Topaloglu H, Moore SA, Gotthardt M, Samuels ME, Gautel M, Ferreiro A (2014) Recessive TTN truncating mutations define novel forms of core myopathy with heart disease

FIGURE 1 Besides hepatotoxicity, other APAP side effects have also been observed in children

, Kim1 expression increased with higher doses of sulfasalazine (Supplemental Figure 6), suggesting a dose-dependent nephrotoxic effect