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L-glutathione is generally considered safe when taken in recommended doses

Upon addition of GSH, a new emission peak at 520 nm emerges and the intensity is rising along with the increase of GSH concentration (Figure 4A)

For instance, in the fibrotic microenvironment where lactate accumulates and is taken up by macrophages and myofibroblasts, p300 has been implicated in promoting lactylation at macrophage-related loci, potentially contributing to the progression of pulmonary fibrosis [81]