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By contrast, the green fluorescence from AsGGT2 N100 -GFP was observed predominantly in the vacuole ( Figure 7B ), indicating that AsGGT2 has a signal sequence for targeting to the vacuole within its N-terminal 100 amino acid residues

PMID: 32274083

X., Ferrans, V

The nonstructural proteins include the polymerases PB1, PB2, and PA, the nucleocapsid protein, the nonstructural protein 1, the nuclear export protein, and the PA-X protein

Their multi-target pharmacology presents a unique opportunity for breakthrough therapies in complex disorders such as AD

Importantly, sulforaphane-mediated NRF2 activation can also be neuroprotective in models of induced epilepsy when administered post-seizure