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Contrary to normal smokers, COPD patients have defects in DNA repair, as documented by very low expression of the double-stranded repair protein Ku86 (Caramori et al

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10.1136/gut.2006.101634 Gut 19 MalfertheinerP.MegraudF.OMorainC.GisbertJ.KuipersE.AxonA.et al (2017)