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In the second step, glutathione synthetase (GS

This conversion can lower intracellular oxidative stress, provided that the HO formed is promptly removed by downstream antioxidant enzymes [47], because HO, although less reactive than O 2 , is still a ROS

10.7150/ijbs.7367 18 Dalle CarbonareL.CominaciniM.TrabettiE.BombieriC.PessoaJ.RomanelliM

Cancer Cell Int 18:24

Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways

Among them, resveratrol, icariin, epigallocatechin-3-gallate, ginsenoside, sinomenine, paeoniflorin, triptolide and paeoniflorin are star natural medicines for the treatment of RA