[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Tkalcevi V.I., Cuzi S., Brajsa K., Mildner B., Bokuli A., Situm K., Perovi D., Glojnari I., Parnham M.J
Preferred scientific spelling Epitalon Common alternative spelling Epithalon Amino-acid sequence Ala-Glu-Asp-Gly Peptide length Four amino-acid residues Common abbreviation AEDG Main research areas Telomeres and pineal biology Human clinical evidence Very limited UK approval No marketing authorisation identified What Is Epithalon Peptide
More receptors does not automatically mean better, as the side effect profile and optimal dosing still need to be established
The peptide also shows benefits in photoaging models, where chronic UV-induced inflammation contributes to ongoing tissue damage
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Clinical trial limitations No pineal peptide has undergone the rigorous Phase I through Phase III clinical trial process required for FDA approval