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After validation, the structures of the HaloTag adducts were deposited in the PDB database under PDB codes 7ZBA (MeTRaQ-G), 7ZBB (TRaQ-G-ctrl) and 7ZBD (TRaQ-G)

Skin biopsy and blood testing are rarely necessary

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However, our data suggest that such inhibitors may have more utility when given in combination with 5FU-based chemotherapy

Research conducted by 4.3 Alleviation of the toxic side effects of drugs 4.3.1 Antineoplastic drugs Anti-cancer agents, including alkylating agents, human epidermal growth factor receptor two receptor blockers, anthracyclines, microtubule modulators, tyrosine kinase inhibitors, histone deacetylase inhibitors, and antimetabolites, are collectively associated with significant cardiotoxicity