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All housing, handling, and experimentation that involved the rats were conducted following the procedures set in place by the National Institutes of Health guide for the care and usage of laboratory animals [2]

and plasmodium knowlesi in monkeys

Acta Ophthalmologica 94:S256

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In therapeutic dosage, paracetamol is largely metabolised by phase II processes (glucuronidation and sulphation) to stable metabolites, but between 5% and 10% also undergoes P450 metabolism to the toxic N -acetyl p-benzoquinoneimine (NAPQI) metabolite (Nelson, 1990) (Figure 8.3)

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