The standard 4-6 weeks on, 2-4 weeks off pattern provides a structured approach even without specific data guiding these intervals
We have found this product works best when used in conjunction with a liposomal glutathione blend, which I discuss below
10.3748/wjg.v23.i48.8465 18 FaghihiH.Mehdi RajaeiS.MehrazinH.GolabdarS.BrooksD
They added GHK-Cu in concentrations of 10 M to 10 M and measured: Collagen synthesis (by radioactive proline incorporation) Non-collagen protein synthesis Cell proliferation What they found: Stimulation of collagen synthesis by 70 % at the optimal concentration of 10 M (1 nM) The effect was NOT dependent on increased proliferation, fibroblasts increased production per cell Background: GHK without copper had a dramatically weaker effect , Cu is critical Reversibility: After removing GHK-Cu, synthesis returned to baseline Why it matters: This is the fundamental mechanistic study that documented the effect of GHK-Cu on collagen
Clinical, Cosmetic and Investigational Dermatology, 10, 147-153
Side Effects and Safety Information Research on side effects of BPC-157 is still developing