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An additional passive, unsaturable absorption pathway exists that is used when the intraintestinal folate concentrations exceed 10 M 209

In these scenarios, the supplement is working "behind the scenes" to neutralise toxins, which might delay the outward benefits you were hoping for

Healthy Effects of Plant Polyphenols: Molecular Mechanisms

How they work: Zinc Oxide and Bismuth Salts are mild astringents and antiseptics that soothe and protect raw, irritated areas

Jomov K, Hudecova L, Lauro P, Simunkova M, Alwasel SH, Alhazza IM, Valko M (2019) A switch between antioxidant and prooxidant properties of the phenolic compounds myricetin, morin, 3,4-dihydroxyflavone, taxifolin and 4-hydroxy-coumarin in the presence of copper(II) ions: a spectroscopic, absorption titration and DNA damage study