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Other rare but serious complications include infection at the injection site (abscess formation) and, in isolated reports, neurological effects

This inhibition prevents the conversion of nicotinamide into 1-methylnicotinamide, effectively rescuing the NAD salvage pathway

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Inflammation persists past week 6

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The absence of a determined lethal dose in rodent studies reflects that acute toxicity testing did not reach a fatal threshold at doses tested, not that the compound has been proven safe at all doses or via all routes over extended periods in any species