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It acts by binding to BCL-W, BCL-2, and BCL-XL, inhibiting their function [102]
Additionally, results of experiments performed on normal volunteers in whom intraepidermal nerve fibers were denervated by the application of capsaicin show that cutaneous autonomic nerve fibers regenerate much faster than sensory nerve fibers (28)
3-MA stands as a commonly employed autophagy inhibitor
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For instance, manifestation of radiation toxicity at the cellular level involves simultaneous activation of various pro-survival and cytotoxic pathways in a ROS-dependent (indirect effect of radiation) and independent (direct effect of radiation) manner [37, 40, 100]