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Tibon NS, Ng CH, Cheong SL (2020) Current progress in antimalarial pharmacotherapy and multi-target drug discovery

The enzymes that attach glutathione to toxins are the glutathione S-transferases, encoded by genes including GSTM1 , GSTT1 , and GSTP1

The peptides will still bind to their receptors, but the downstream cascade they're designed to trigger gets suppressed at multiple points in the pathway

This end-of-cycle dip is normal

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REMS) and additionally designates each epoch as likely or unlikely to contain artifacts