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doi: 10.1155/2021/6657434 17 PisoschiAMPopA
- Sndrome de intestino permeable: normalizacin de uniones estrechas (occludina, claudina-1, ZO-1)
Systemic metabolic alterations and their relationship to neuropsychiatric symptomatology PAIS, including long COVID, as well as CFS and IMD, share the characteristic of systemic metabolic disturbances, which may be a sign of underlying multi-organ inflammation and exhaustion [31], and consequently may contribute to neuropsychiatric symptomatology, as many metabolites can cross the bloodbrain barrier (BBB) [30, 58] (e.g., short chain fatty acids (SCFAs) derived from the gut microbiota such as acetate [40], amino acids such as tryptophan [52] and also carnitine/acetylcarnitine can cross the BBB via transporters [59])
Levin, M
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2025 Oct 7;122(40):e2502841122
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