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First of all, there may be difference in the intensity of ROS formation by paraquat and/or in ROS suppression by antioxidant, between in vitro cell line and cells in physiologic state

It does not necessarily require enzyme catalysis to function, and can be applied in aqueous media under a wide range of conditions

doi: 10.7326/0003-4819-137-12-200212170-00007 69 PangC.ZhengZ.ShiL.ShengY.WeiH.WangZ.et al

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Toxicity of intermediates was higher than that of the parent molecule (assessment with the use of Microtox bioassay)

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