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[5] In essence, it releases the brake on the pituitary, causing a surge in the patients own GH output

This feedback loopfibrosis enabling SIBO, and SIBO amplifying fibrosistypifies the fibro-inflammatory circuit that underlies gastrointestinal involvement in SSc

Individuals with pituitary disorders should exercise particular caution, as the peptide directly affects pituitary function

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One reason could be that in vivo-studies are much more expensive and sophisticated