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hCG directly stimulates Leydig cells to produce and release intratesticular testosterone by binding to the luteinizing hormone/choriogonadotropin receptor (Rizzuti et al., 2023)

Excessive generation of ROS within ovarian, adipose, and hepatic tissues overpowers antioxidant defenses, leading to oxidative damage of lipids, proteins, and mitochondrial DNA (74)

UPF intake during critical pre- or perinatal periods may also drive risk via epigenetic modifications

Guided Crystalline Regeneration When applied to an early carious lesion, P11-4 diffuses into the subsurface demineralized zone and self-assembles into a fibrous matrix

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