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Transgenic APPswe/PSEN1-dE9 mice spontaneously deposited more abnormal plaques than the wild-type ones, and the plaque reduction effect was not apparent when conducting sequential inhibitor administration

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Much of this initial loss represents water and glycogen rather than pure fat loss

Male mice lacking SELENOP have reduced fertility, less selenium, and lower glutathione peroxidase activity [2]

A major obstacle to effective treatment is the inability of many neuroprotective agents to reach the brain at therapeutically relevant concentrations due to poor bioavailability and the restrictive nature of the bloodbrain barrier

The benzyl alcohol inhibits microbial growth, allowing the water to be used for multiple reconstitutions from the same vial