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A phase I dose escalation and expansion trial of the next-generation oral SERD camizestrant in women with ER-positive, HER2negative advanced breast cancer: SERENA-1 monotherapy results

HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis

(Detoxification) - : GSH (Al, Cu) acetaldehyde Thiol-metal Thiol-carbonyl - Glyoxalase System: GSH Glyoxalase 1 2 Methylglyoxal () () 5

Decreased SOD activity is correlated with heightened levels of oxidative damage, encompassing membrane lipid peroxidation, protein carbonylation, and DNA fragmentation [32]