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The 4 mg arm landed near the territory that semaglutide occupies, the 8 mg arm matched what tirzepatide achieves at its top dose, and the 12 mg arm went somewhere no single or dual agonist had reached in a trial of that size

This has nothing to do with wellness, said Bert Mandelbaum, MD, sports medicine specialist, orthopedic surgeon, and co-director of the Regenerative Orthobiologic Center at Cedars-Sinai Orthopedics in Los Angeles

Unfortunately, its also one of the vitamins that people are most likely to be deficient in, especially if they are vegetarian or vegan, are over 50, or have conditions that affect absorption