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All plants displayed localized necrotic lesions (HR) in TMV-inoculated leaves, the extent of HR being most severe in NahG tobacco, while GSH-overproducing CEMK-9 and TRI-2 lines displayed the weakest HR

4 In addition, NAC must be administered at high doses due to its low bioavailability, but high-dose NAC may increase the risk of adverse reactions

Clinica Chimica Acta 279: 114