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By age 60, that level goes down to just 80 ng/mL

Neurotoxicology 23:367374 Kim JS, Kim J-M, Jeong-Ja O, Jeon BS (2010) Inhibition of inducible nitric oxide synthase expression and cell death by ()-epigallocatechin-3-gallate, a green tea catechin, in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine mouse model of Parkinsons disease

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Anti-inflammatory peptides reducing acute inflammation

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Its generally considered usable for several weeks after opening when stored correctly, though this can vary depending on the specific product and manufacturer guidance