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However, baseline homocysteine levels tend to be lower in people with Down syndrome than people without Down syndrome
Potential Risks Risks depend on the exact product and your health history, but can include: Injection-site reactions (pain, bruising, swelling) Allergic or hypersensitivity reactions (rare but possible) Product-quality risks if the mixture is compounded and not prepared under appropriate standards For B12 injections specifically, review FDA-approved labeling and warnings (see the FDA prescribing information for cyanocobalamin injection )
[PubMed] [Google Scholar] Graham 2007 Graham ID, Jette N, Tetroe J, Robinson N, Milne S, Mitchell SL
Start with 0.5 percent and increase to 1 or 2 percent if tolerance is good and results warrant intensification
Consider supplementation in asymptomatic patients with risk factors (see Table 2: Patient Risk Factors Associated with Folate Deficiency below) consider supplementation