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Therefore, it seems that the prepared topical liposomal preparation was promising in melasma treatment (Kusumawardani et al., 2019)
In the presence of elevated oxidative stress, such as in iron overload, sarcoplasmic reticulum Ca 2+ leaks through the Ca 2+ release channels (62), sarcoendoplasmic reticulum Ca 2+ -ATPase activity is inhibited, the sodium-calcium exchanger currents are elevated (63), and L-type calcium channels are reduced (64, 65)
Aside from dimercaprol, sodium-calcium EDTA, DMPS, DMSA and its analogues, there are other chelators that are used in clinical therapy, namely deferoxamine (DFO) and D-Penicillamine
Detoxification: It aids in cleansing the liver and removing toxins from the body
ab125066, Abcam), and SLC7A11 (1:200