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Acknowledgements This work is funded by the National Natural Science Foundation of China (81530028

Do not use if you have active cancer, diabetic retinopathy, or are pregnant or breastfeeding

A dose-dependent pattern was observed for dry mouth and insomnia

These include: Molecular interactions between receptors Cell signalling pathways Pharmacokinetics Metabolism Human clinical trials under strict control Biomarker reactions Site-specific effects The developments in the field of peptide chemistry might lead to enhanced molecular stability, selectivity for receptors, and analytical techniques

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10.3390/nu16020182 66 CassaniE.PriviteraG.PezzoliG.PusaniC.MadioC.IorioL.et al