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Infusion of obese Zucker rats as well as lean littermates with AICAR decreases plasma TAG and FA concentrations, as well as glycerol turnover (37), whereas mice lacking the AMPK-alpha2 subunit have been shown to have increased adiposity and weight gain (98, 131)

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S-acetyl-glutathione attenuates carbon tetrachloride-induced liver injury by modulating oxidative imbalance and inflammation