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ALINA: a phase III study of alectinib versus chemotherapy as adjuvant therapy in patients with stage IB-IIIA anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC)

doi: 10.1016/0006-2952(95)02436-0 10 CapuanoA.ScavoneC.RacagniG.ScaglioneF

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Exogenous MOTS-c is now in early-phase human trials

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The mechanism of action is multifactorial, directly or indirectly upregulating cell growth, proliferation, survival, angiogenesis, and anti-inflammation pathways