This was conducted with brain (or vein) images for healthy rats, and then for both the control (saline) group and the treated (BPC 157) group of rats at the same intervals after the application and at the time of sacrifice
Thus, it seems that DSIP may indeed play a role in altering physiology in preparation of the body for sleep, as some of it effects occur before neurological and behavioral signs of sleep
This can result in: Reduced pain Enhanced joint stability Improved range of motion Quicker return to normal activity Ideal Candidates for Prolotherapy Prolotherapy is most effective in Type I to Type III AC separations , especially when: Pain persists beyond 4-6 weeks of conservative care There is evidence of ligament laxity or instability The patient prefers a non-surgical option The patient is physically active and motivated for recovery The Prolotherapy Treatment Protocol for AC Separation Pre-Treatment Evaluation Prior to treatment, a comprehensive musculoskeletal exam is conducted to assess: Joint instability Tenderness and ligament integrity Shoulder biomechanics Imaging (X-ray or ultrasound) to classify injury severity Injection Technique Patient Positioning: Seated or supine with shoulder exposed Site Preparation: Skin cleaned with antiseptic
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doi: 10.1002/1097-0142(19930701)72:1 3.0.co;2-q
